Prior to sclerotherapy, you should avoid certain medications. Talk to your doctor about all medicines (including over-the-counter drugs, herbs, and dietary supplements) you are taking. If you need to take an antibiotic before sclerotherapy, contact your doctor. No lotion should be applied to the legs before the procedure.
Some doctors recommend avoiding aspirin, ibuprofen (such as Advil, Motrin, and Nuprin) or other anti-inflammatory drugs for 48-72 hours before sclerotherapy. Tylenol, however, should not affect this procedure.